Phospho-creb
WebSelected: P-CREB Antibody $ 1,795.00 $ 895.00 1,795.00 $ 895.00. P-CREB Antibody quantity WebCyclic AMP response element binding protein (CREB) is a basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in …
Phospho-creb
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WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity … WebHuman Phospho-CREB (S133) Antibody Summary Species Reactivity Human Specificity Detects human CREB when phosphorylated at S133. Source Monoclonal Mouse IgG 2A Clone # 702710 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Phosphopeptide containing the human CREB S133 site Formulation
WebApr 11, 2024 · The classical PKC/ERK/CREB signaling pathway is involved in the synthesis of pituitary TSH . To evaluate whether the PKC/ERK/CREB signaling pathway mediates the regulation of TSH with CK1α, we analyzed the phosphorylation levels of PKC, ERK, and CREB in the mouse pituitary gland after treatment with 1 mg/mL D4476 or 5 mg/mL pyrvinium. WebMar 29, 2024 · The CREB binding domain, referred to as KIX, is α helical and binds to an unstructured kinase-inducible domain in CREB following phosphorylation of CREB at Ser-133. Phospho-Ser-133 forms direct contacts with residues in KIX, and these contacts are further stabilized by hydrophobic residues in the kinase-inducible domain which flank …
WebFeb 17, 2009 · To test whether any CREB potentiating compounds identified in the screen acted on PKA, compounds were tested in a PKA enzyme based assay that measured phosphorylation of a target peptide. 8-bromo-cAMP and 8-(4-chlorophenylthio)-cAMP, which are cAMP analogues, were found to be active in the primary CRE-β-lactamase screen, both … WebMar 29, 2024 · The CREB binding domain, referred to as KIX, is α helical and binds to an unstructured kinase-inducible domain in CREB following phosphorylation of CREB at Ser …
WebAnti-phospho-CREB (Ser133) Antibody, clone 10E9 is a Mouse Monoclonal Antibody for detection of phospho-CREB (Ser133) also known as active transcription factor CREB & has been validated in WB, ELISA. ELISA: Recommended at 0.05 μg/mL by an independent laboratory. Research Category Epigenetics & Nuclear Function Research Sub Category
WebCyclic AMP response element binding protein (CREB) is a constitutive transcription factor that activates transcription following stimulus-dependent phosphorylation at Ser133, implicated in synaptic plasticity and neuronal survival pathways. poof sound effectWebPhosphorylation of CREB occurs via p44/42 MAP kinase and p90RSK, and via p38 MAP kinase and MSK1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in ... shaping rbt exampleWebAn immobilized capture antibody specific for CREB binds both phosphorylated and unphosphorylated CREB. After washing away unbound material, a biotinylated detection antibody is used to detect only phosphorylated receptor, utilizing a standard HRP format. Complete Your Research Human Phospho-CREB (S133) Antibody Cat # MAB6906R DNQX … shaping rate fttpWebKnockdown of CREB (cAMP response element-binding protein) promotes apoptosis in pre-B acute lymphoblastic leukemia cells by preventing prosurvival signals. It controls the … poof storyWebTime-dependent induction of CREB phosphorylation in the hippocampus by the endogenous cannabinoid Masako Isokawa Department of Biological Sciences, The University of Texas at Brownsville, Brownsville TX 78520 Abstract The involvement of the endogenous cannabinoid system has been implicated in the rewarding actions of several drugs of abuse. shaping rbt definitionCREB-TF (CREB, cAMP response element-binding protein) is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements (CRE), thereby increasing or decreasing the transcription of the genes. CREB was first described in 1987 as a cAMP-responsive transcription factor regulating the somatostatin gene. shaping reinforcementWebJan 17, 2024 · PKA-mediated phosphorylation of CREB. This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped … shaping rocks with a dremel