Ctr copper transporter family protein

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August undefined, 2024

WebRecently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in … WebApr 11, 2024 · Arabidopsis copper transport protein COPT2 participates in the cross talk between iron deficiency responses and low-phosphate signaling. Plant Physiol., 162 (2013), ... Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol., 11 (2011), p. 69. View in Scopus Google Scholar

Copper homeostasis in grapevine: Functional characterization …

WebMar 1, 2003 · Recently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in the plasma membrane as a homo-trimer. WebSolute carrier family. The solute carrier ( SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1] [2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee ( HGNC) and is the basis for the ... chr toyota price in south africa

Arabidopsis COPT1 copper transporter uses a single histidine to ...

WebThe reported Cu transporters are mainly from the COPT/Ctr protein family. Cu might be co-transported by COPT2, COPT3, and COPT4 with COPT6. ... Yuan M, Li X, Xiao J, Wang S (2011) Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol 11(1):69 WebFigure 1. Bioinformatic analysis identifies C. thermophilum copper transporters. A, model showing a homotrimeric Ctr1/Ctr3 family protein complex with key Cys and Met residues involved in Cu + transport connected with a dashed red circle and key Gly residues involved in trimer stability via transmembrane helical packing highlighted with a red box. … WebApr 2, 2014 · Some pieces of evidence reported that Cu can be also taken up by other bivalent cations transporters, as the Natural Resistance Associated Macrophage Proteins (NRAMP), Zrt-and Irt-like proteins... chr toyota scheda tecnica

Eukaryotic CTR Copper Uptake Transporters Require Two …

SLC31 (CTR) Family of Copper Transporters in Health and Disease

WebDec 1, 2015 · The COPT/Ctr family belongs to a highly conserved Ctr-like Cu transporter family. Most COPT/Ctr transporters contain 3 TMDs: TMD1, TMD2, and TMD3. The N terminus of most COPT/Ctr transporters includes methionine motifs involved in Cu binding that is important for facilitated import (Beaudoin et al., 2011). WebJan 5, 2024 · Enables copper ion transmembrane transporter activity. Involved in cellular copper ion homeostasis; copper ion transport; and regulation of heart rate. Located in plasma membrane. Is expressed in adult head. Orthologous to several human genes including SLC31A1 (solute carrier family 31 member 1). [provided by Alliance of … chr toyota neufWebJul 24, 2024 · Naturally, this localization of the receptors requires the transport of monovalent copper from the plasma membrane via the cytoplasm to the apoproteins in the ER-Golgi membranes. The identity of the copper carriers involved in this task and their cellular routes are not yet completely known. chr toyota new

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Ctr copper transporter family protein

Copper transport protein (Ctr1) levels in mice are tissue …

Webthe SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights … WebApr 21, 2011 · The copper (Cu) transporter (COPT/Ctr) gene family has an important role in the maintenance of Cu homeostasis in different species. The rice COPT-type gene family consists of seven members (COPT1 to COPT7). However, only two, COPT1 and COPT5, have been characterized for their functions in Cu transport. Here we report the …

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WebJan 5, 2024 · COPT5copper transporter 5 [ Arabidopsis thaliana(thale cress) ] Gene ID: 832188, updated on 5-Jan-2024 Download Datasets Gene Sequences (FASTA) … WebOct 19, 2015 · These transport proteins are thought to have evolved from ‘half-transporters’ containing a single repeat via gene duplication and subsequent fusion 28. …

WebSep 25, 2024 · CTR1 belongs to a family of Copper Transporters that has at least six members (CTR1-6) among various organisms. Structural and functional divergence of the CTRs from lower organisms to mammals shed light on how the regulation of this protein family is modulated depending on the requirement and availability of copper. WebDec 13, 2024 · Gene Summary Copper transporter 1A ( Ctr1A) encodes a plasma membrane protein that functions as a copper transporter. It is required to drive neuropeptide maturation during normal growth and development. [Date last reviewed: 2024-03-07] ( FlyBase Gene Snapshot ) All Summaries Gene Snapshot Gene Group Key …

WebJun 30, 2024 · COPT, a conserved family of membrane proteins that function as copper transporters, can cope with copper deficiency and excess. In addition to Cu transport, … WebNov 1, 2006 · CTR1 belongs to the CTR (or SLC31A) family that includes CTR1/2 and P-type copper transporting ATPases (ATP7A and B). It is a 23-kDa channel-like transporter which has a unique pore for the transport of copper and three trans-membranes domains that oligomerize to form a functional trimer [85].

WebJul 21, 2014 · The family of proteins responsible for the transport of Cu in the reduced form is the COPT transport protein (copper transporter protein). These proteins are formed by five...

WebSep 12, 2007 · High-affinity cellular copper uptake is mediated by the CTR (copper transporter) 1 family of proteins. The highly homologous hCTR (human CTR) 2 protein has been identified, but its function in copper uptake is currently unknown. To characterize the role of hCTR2 in copper homoeostasis, epitope-tagged hCTR2 was transiently … chr toyota pantipWebApr 1, 2014 · Copper (Cu) is an essential micronutrient for all eukaryotes because it participates as a redox active cofactor in multiple biological processes, including mitochondrial respiration, photosynthesis, oxidative stress protection, and iron (Fe) transport. In eukaryotic cells, Cu transport toward the cytoplasm is mediated by the … chr toyota redWebMar 1, 2004 · A different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all … chr toyota silverWebOct 1, 2024 · The moss Physcomitrium (Physcomitrella) patens is a bryophyte that provides genetic information about the adaptation to the life on land by early Embryophytes and is a reference organism for comparative evolutionary studies in plants. Copper is an essential micronutrient for every living organism, its transport across the plasma membrane is … derogatory term for spastic diplegiaWebCtr copper transporter family. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress … chr toyota ratingWebJun 24, 2003 · A different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all … chr toyota reviewWebMembers of the copper uptake transporter (CTR) family from yeast, plants, and mammals including human are required for cellular uptake of the essential metal copper. Based on biochemical data, CTRs have three … chr toyota seat covers