WebApr 30, 2011 · Cisplatin, cis-diamminedichloro-platinum(II) or [(NH 3) 2 PtCl 2], is one of the most widely used antitumor drugs and is most active against a variety of tumors, especially testicular and ovarian cancers [1–3].However, its clinical success is limited by severe side effects which have led to the development of second-generation platinum compounds … http://www.chem.uiuc.edu/rogers/Text7/Tx73/tx73.html

Torsion angles (deg) for cisplatin. Download Table - ResearchGate

Webthe bond lengths and angles. The application of method . Figure 2. View of the seven non-equivalent and non-enantiomorphic conformations of cisplatin arising from the … WebA bond angle is the angle between any two bonds that include a common atom, usually measured in degrees. A bond distance (or bond length) is the distance between the nuclei of two bonded atoms along the straight line joining the nuclei. Bond distances are measured in Ångstroms (1 Å = 10 –10 m) or picometers (1 pm = 10 –12 m, 100 pm = 1 Å). phitomel

Transplatin - an overview ScienceDirect Topics

WebCisplatin also plays an interesting role in the history of chemistry. First synthesized in the 1800s, long before anyone thought of using it against cancer, cisplatin was a target … WebFig. 4 displays the ORTEP diagrams of their molecular structures whereas the main crystallographic data and selected bond distances and angles can be found in the ESI† section (Tables S2–S3†). All compounds crystallize in the monoclinic system, space group C 12/ c 1 ( 1 ), P 12 1 / c 1 ( 3 , 7 ) or P 12 1 / n ( 5 , 6 ) with exception of ... WebFeb 19, 2024 · Table 1. Force field parameters for cisplatin: bond force constants 𝑘𝑏 , equilibrium distances 𝑅0 , angle force constants 𝑘𝑎 , equilibrium angles 𝜃0 , atomic charges 𝑞 and Lennard-Jones parameters 𝑅𝑚𝑖𝑛 2⁄ and ε. - "The Permeation Mechanism of Cisplatin through a Dioleoylphosphocholine Bilayer." phit onc